Centers for Disease Control - Meningitis and Vaccine Preventable Diseases Branch, USA

The Centers for Disease Control and Prevention (CDC) is the principal public health agency in the United States. While its primary responsibilities are domestic, CDC supports health promotion and disease prevention efforts worldwide.

CDC has a long history of work in meningococcal disease epidemiology and prevention, and serves as a WHO Collaborating Center on Meningococcal Disease.

The work of CDC encompasses vaccine development and evaluation, surveillance, outbreak preparedness and response, risk factor studies, carriage studies, development and standardisation of diagnostic and vaccine assays, and bacteriologic and molecular characterisation of meningococcal isolates.

Important contributions made by CDC include monitoring the effectiveness of meningococcal polysaccharide A vaccine, development of trans-isolate medium for improved laboratory confirmation of meningococcal disease, determination of predictors of immunity associated with a large W135 epidemic in Burkina Faso, and development and evaluation of novel molecular identification techniques.

CDC scientists currently serve as primary advisors on statistical methods for the Meningitis Vaccine Project (MVP), perform all ELISA serologic assays for the MVP pre-licensure trials, and serve as primary technical advisors for the evaluation of the first nationwide introduction of the MVP conjugate vaccine in Burkina Faso.

CDC - Centers for Disease Control and Prevention